The secretome of microglia induced by IL-4 of IFN-γ differently regulate proliferation, differentiation and survival of adult neural stem/progenitor cell by targeting the PI3K-Akt pathway
Xue Jiang, Saini Yi, Qin Liu, Jinqiang Zhang
Topics & Concepts
MicrogliaNeurogenesisProgenitor cellCell biologyBiologyNeural stem cellPI3K/AKT/mTOR pathwayCellular differentiationStem cellSignal transductionImmunologyInflammationBiochemistryGeneNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsImmune cells in cancer