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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

Emeline Dierge, Elena Debock, Céline Guilbaud, Cyril Corbet, Éric Mignolet, Louise Mignard, Estelle Bastien, Chantal Dessy, Yvan Larondelle, Olivier Féron

2021Cell Metabolism494 citationsDOIOpen Access PDF

Topics & Concepts

Polyunsaturated fatty acidLipid peroxidationChemistryBiochemistryCancer researchBiologyOxidative stressFatty acidCancer, Lipids, and MetabolismFerroptosis and cancer prognosisCancer, Hypoxia, and Metabolism
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects | Litcius