Three metal complexes with a pyridyl Schiff base: cytotoxicity, migration and mechanism of apoptosis
Feiya Zhou, Fangxin Gao, Qinghua Chang, Xianfeng Yang, Li‐Li Liang
Abstract
Three metal complexes were synthesized with a pyridyl Schiff ligand. 2 had the best antiproliferative activity against SMMC-7721 cells and 3 had the best antiproliferative activity against MDA-MB-231 cells with single-digit IC 50 values.
Topics & Concepts
CytotoxicityApoptosisChemistryCell cycleCisplatinCytotoxic T cellIn vitroSchiff baseLigand (biochemistry)Cell growthMolecular biologyCancer cellStereochemistryCell biologyBiochemistryBiologyReceptorCancerChemotherapyGeneticsMetal complexes synthesis and propertiesSynthesis and Characterization of Heterocyclic CompoundsMetal-Organic Frameworks: Synthesis and Applications