Development of Electrochemical Platform Based on Molecularly Imprinted Poly(methacrylic acid) Grafted on Iniferter‐modified Carbon Nanotubes for 17β‐Estradiol Determination in Water Samples
Gabriel Lopes Marques, Luana Rianne Rocha, Maiyara Carolyne Prete, Felipe Augusto Gorla, Dayana Moscardi dos Santos, Mariana Gava Segatelli, César Ricardo Teixeira Tarley
Abstract
Abstract This paper describes the development of a new electrochemical sensor for 17β‐estradiol (E2) determination based on glassy carbon electrode (GCE) modified with molecularly imprinted polymer grafted onto iniferter‐multiwall carbon nanotubes surface (MIP‐MWCNT) and dihexadecyl‐hydrogen‐phosphate (DHP). The electrochemical method was based on closed‐circuit preconcentration of E2 in 0.1 mol L −1 phosphate buffer (pH 7.0) during 500 s. Upon preconcentration, E2 was determined by differential pulse voltammetry (DPV) exhibiting a limit of detection of 0.01 μmol L −1 . The sensor exhibited higher selectivity toward E2 and it was applied for E2 determination in natural water samples, with accuracy attested by HPLC‐DAD.