Effects of Polystyrene Microplastics on Human Kidney and Liver Cell Morphology, Cellular Proliferation, and Metabolism
Kerestin E. Goodman, Timothy Hua, Qing‐Xiang Amy Sang
Abstract
), thus reducing the potential of SOD2 and CAT to detoxify ROS. These adverse effects of PS-MPs on human kidney and liver cells suggest that ingesting microplastics may lead to toxicological problems on cell metabolism and cell-cell interactions. Because exposing human kidney and liver cells to microplastics results in morphological, metabolic, proliferative changes and cellular stress, these results indicate the potential undesirable effects of microplastics on human health.
Topics & Concepts
Viability assayFlow cytometryKidneyCell cultureMicroplasticsCell growthCellChemistryHepatic stellate cellBiologyTrypan blueMolecular biologyCell biologyBiochemistryEndocrinologyEnvironmental chemistryGeneticsMicroplastics and Plastic PollutionEffects and risks of endocrine disrupting chemicalsbiodegradable polymer synthesis and properties