CAFs secrete CXCL12 to accelerate the progression and cisplatin resistance of colorectal cancer through promoting M2 polarization of macrophages
Hang Jiang, Haijue Ge, Yuanyuan Shi, Fang Yuan, Hongqin Yue
Topics & Concepts
ChemokineCancer researchCisplatinCell growthMacrophage polarizationTumor microenvironmentCell cultureCell migrationColorectal cancerMTT assayImmunofluorescenceBiologyImmunologyMacrophageMedicineCancerIn vitroInflammationInternal medicineAntibodyTumor cellsBiochemistryChemotherapyGeneticsImmune cells in cancerCancer, Stress, Anesthesia, and Immune ResponseCancer Cells and Metastasis