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Response to Comment on “Impact of neurodegenerative diseases on human adult hippocampal neurogenesis”

Julia Terreros‐Roncal, Elena P. Moreno‐Jiménez, Miguel Flor‐García, C. B. Rodríguez-Moreno, Mariela F. Trinchero, Berenice Márquez‐Valadez, Fabio Cafini, Alberto Rábano, Marı́a Llorens-Martı́n

2022Science14 citationsDOIOpen Access PDF

Abstract

Alvarez-Buylla and colleagues provide an alternative interpretation of some of the data included in our manuscript and question whether well-validated markers of adult hippocampal neurogenesis (AHN) are related to this phenomenon in our study. In Terreros-Roncal et al ., reconstruction of the main stages of human AHN revealed its enhanced vulnerability to neurodegeneration. Here, we clarify ambiguities raised by these authors.

Topics & Concepts

NeurogenesisNeurodegenerationHippocampal formationNeuroscienceVulnerability (computing)HippocampusPsychologyBiologyMedicinePathologyDiseaseComputer scienceComputer securityNeurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research
Response to Comment on “Impact of neurodegenerative diseases on human adult hippocampal neurogenesis” | Litcius