Chromatography–Mass Spectrometry Analysis for the Determination of the Markers and Biomarkers of Chemical Warfare Agents
И. В. Рыбальченко, T. M. Baigil’diev, И. А. Родин
Abstract
This paper considers publications devoted to the development and improvement of methods for the determination of markers and biomarkers of chemical warfare agents (CWAs) using various combinations and modifications of gas and liquid chromatography–mass spectrometry. Attention is focused on the importance of choosing an optimal analysis strategy and optimizing sample preparation procedures and operating modes of analytical instruments. Published data on the selection of characteristic markers of organophosphorus CWAs and sulfur mustard gas and methods for their determination are summarized.
Topics & Concepts
ChemistryChemical Warfare AgentsMass spectrometryChromatographyGas chromatographyGas chromatography–mass spectrometrySulfur mustardSample preparationBiochemical engineeringOrganic chemistryToxicityEngineeringPesticide Exposure and ToxicityInsect and Pesticide ResearchEnvironmental Toxicology and Ecotoxicology