Berberine mediates tumor cell death by skewing tumor-associated immunosuppressive macrophages to inflammatory macrophages
Dhruvi Shah, Naveen Challagundla, Vaidehi Dave, Ashok Patidar, Bhaskar Saha, Manish Nivsarkar, Varsha B. Trivedi, Reena Agrawal-Rajput
Topics & Concepts
BerberineMacrophage polarizationTumor microenvironmentMacrophageCancer researchImmune systemCytotoxic T cellAdipose tissue macrophagesTumor necrosis factor alphaMyeloid-derived Suppressor CellMelanomaChemistryBiologyImmunologyIn vitroCancerPharmacologyBiochemistryWhite adipose tissueGeneticsSuppressorAdipose tissueBerberine and alkaloids researchImmune cells in cancerAlkaloids: synthesis and pharmacology