Snail1 expression in endothelial cells controls growth, angiogenesis and differentiation of breast tumors
David Cabrerizo Granados, Raúl Peña, Laura Palacios, Laura Carrillo-Bosch, Josep Lloreta, Laura Comerma, Mar Iglesias, Antonio Garcı́a de Herreros
Abstract
: These findings show a novel role for Snail1 in endothelial cell activation and demonstrate that these cells impact not only on angiogenesis, but also on tumor onset and phenotype.
Topics & Concepts
AngiogenesisCancer researchCell biologyBiologyCancer Cells and MetastasisBone and Dental Protein StudiesCancer, Hypoxia, and Metabolism