<i>In vivo</i> bioimaging and detection of endogenous hypochlorous acid in lysosome using a near-infrared fluorescent probe
Jian Jiang, Shaocai Wang, Sai Wang, Yinshuang Yang, Xiuli Zhang, Wenjun Wang, Xu Zhu, Mingxi Fang, Yaozeng Xu
Abstract
imaging towards mice with osteoarthritis. As a result, the probe FNIR-HOCl is extremely promising as a biological tool for revealing the roles of HOCl in various physiological and pathological contexts.
Topics & Concepts
Hypochlorous acidFluorescenceIn vivoChemistryLysosomeEndogenyInfraredBiophysicsBiochemistryBiologyOpticsEnzymePhysicsBiotechnologyMolecular Sensors and Ion DetectionNeutrophil, Myeloperoxidase and Oxidative MechanismsNitric Oxide and Endothelin Effects