New cyanopyridine-based scaffold as PIM-1 inhibitors and apoptotic inducers: Synthesis and SARs study
Amel M. Farrag, Mona H. Ibrahim, Ahmed B. M. Mehany, Magda M. F. Ismail
Topics & Concepts
ChemistryCytotoxicityCytotoxic T cellApoptosisMTT assayKinaseIn vitroDocking (animal)IC50Cell growthCell cultureBiochemistryStereochemistryBiologyGeneticsNursingMedicineCancer Mechanisms and TherapySynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds