Litcius/Paper detail

lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep

Xiaolei Yao, Xiaoxiao Gao, Yongjin Bao, M.A. El-Samahy, Jinyu Yang, Zhibo Wang, Xiaodan Li, Guomin Zhang, Yanli Zhang, Wujun Liu, Feng Wang

2021Molecular Therapy — Nucleic Acids52 citationsDOIOpen Access PDF

Abstract

transactivation and TGF-β pathway inhibition and promotion of GC apoptosis in Hu sheep. These findings provide insights into the mechanisms underlying prolificacy in sheep.

Topics & Concepts

BiologyGene silencingFollicular phaseLong non-coding RNATransactivationApoptosisDownregulation and upregulationCell biologyTranscription factorCancer researchGeneGeneticsCancer-related molecular mechanisms researchReproductive Physiology in LivestockGenetic and phenotypic traits in livestock