Enantioselective synthesis of chiral β-hydroxy sulfones<i>via</i>manganese catalyzed asymmetric hydrogenation
Jiaying He, Wenhao Mao, Jie Lin, Yongzhen Wu, Lingxin Chen, Pengtao Yang, Dingguo Song, Peixi Zhu, Weihui Zhong, Fei Ling
Abstract
The first example of manganese catalyzed asymmetric hydrogenation of β-keto sulfones for the construction of chiral β-hydroxy sulfones with up to 97% yield and 97% ee.
Topics & Concepts
Enantioselective synthesisChemistryManganeseCatalysisAsymmetric hydrogenationYield (engineering)Organic chemistryCombinatorial chemistryMetallurgyMaterials scienceAsymmetric Hydrogenation and CatalysisSurface Chemistry and CatalysisCatalysis for Biomass Conversion