Dietary fiber intake and fecal short-chain fatty acid concentrations are associated with lower plasma lipopolysaccharide-binding protein and inflammation
Melisa A. Bailey, Sharon V. Thompson, Annemarie R. Mysonhimer, Jessica N. Bennett, James J. Vanhie, Michael De Lisio, Nicholas A. Burd, Naiman A. Khan, Hannah D. Holscher
Abstract
Dietary fiber intake may reduce the inflammation associated with obesity and metabolic disease. Our cross-sectional analysis revealed that dietary fiber intake and fecal short-chain fatty acids are inversely associated with lipopolysaccharide-binding protein, a marker of systemic inflammation. In addition, plasma interleukin-6 and C-reactive protein were positively related to markers of adiposity.
Topics & Concepts
ButyrateFecesInflammationInternal medicineShort-chain fatty acidC-reactive proteinSystemic inflammationEndocrinologyPropionateLipopolysaccharideDietary fiberLipopolysaccharide binding proteinChemistryMedicineFood scienceBiologyBiochemistryAcute-phase proteinMicrobiologyFermentationGut microbiota and healthDiet and metabolism studiesNutritional Studies and Diet