In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
Zeyu Chen, Eri Arai, Omar Khan, Zhen Zhang, Shin Foong Ngiow, Yuan He, Hua Huang, Sasikanth Manne, Zhendong Cao, Amy E. Baxter, Zhangying Cai, Elizabeth Freilich, Mohammed A. Ali, Josephine R. Giles, Jennifer E. Wu, Allison R. Greenplate, Mohamed S. Abdel-Hakeem, Qingzhou Chen, Makoto Kurachi, Kito Nzingha, Viktoriya Ekshyyan, Divij Mathew, Zhuoyu Wen, Nancy A. Speck, Alexis Battle, Shelley L. Berger, E. John Wherry, Junwei Shi
Topics & Concepts
BiologyCRISPRIn vivoCancerCD8Cancer researchVirologyGeneticsComputational biologyGeneImmune systemCRISPR and Genetic EngineeringCAR-T cell therapy researchT-cell and B-cell Immunology