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Enhancement of biological properties in casein protein through functionalization with cinnamaldehyde <i>via</i> Schiff base bonding: antibacterial and antioxidant effects

Aisha Hendy, Nazly Hassan, Jehan El-Nady, Amal S. I. Ahmed, Rabab M. Abou Shahba, Tamer M. Tamer

2025RSC Advances7 citationsDOIOpen Access PDF

Abstract

)], showcasing its potential as an antimicrobial agent. Antioxidant tests demonstrated enhanced scavenging abilities, suggesting protective effects against oxidative stress. Furthermore, preliminary hemocompatibility assessments indicated that the modified protein is non-toxic to human blood cells, underscoring its suitability for biomedical applications. Collectively, these findings suggest that cinnamaldehyde-functionalized casein holds promise for advancing healthcare materials.

Topics & Concepts

CinnamaldehydeSchiff baseSurface modificationChemistryCaseinAntioxidantCombinatorial chemistryBase (topology)Organic chemistryPolymer chemistryPhysical chemistryMathematical analysisCatalysisMathematicsProtein Hydrolysis and Bioactive PeptidesProteins in Food SystemsAntimicrobial Peptides and Activities