Rational design of a “dual lock-and-key” supramolecular photosensitizer based on aromatic nucleophilic substitution for specific and enhanced photodynamic therapy
Kun‐Xu Teng, Li‐Ya Niu, Yan‐Fei Kang, Qing‐Zheng Yang
Abstract
experiments have demonstrated that BIBCl-PAE NPs are effective in targeting and inhibiting carcinoma. BIBCl-PAE NPs show superior anticancer efficiency relative to non-activatable controls.
Topics & Concepts
Photodynamic therapyPhotosensitizerSupramolecular chemistryRational designLock (firearm)Key (lock)ChemistryDual (grammatical number)Combinatorial chemistryNucleophilic substitutionSubstitution (logic)NanotechnologyPhotochemistryComputer scienceMaterials scienceOrganic chemistryMoleculeEngineeringPhilosophyLinguisticsMechanical engineeringComputer securityProgramming languageNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsPhotodynamic Therapy Research Studies