High versus low positive end-expiratory pressure (PEEP) levels for mechanically ventilated adult patients with acute lung injury and acute respiratory distress syndrome
Roberto Santa Cruz, Fernando Villarejo, Célica Irrazábal, Agustín Ciapponi
Abstract
In patients with acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), mortality remains high. These patients require mechanical ventilation, which has been associated with ventilator-induced lung injury. High levels of positive end-expiratory pressure (PEEP) could reduce this condition and improve patient survival. This is an updated version of the review first published in 2013.
Topics & Concepts
MedicineARDSPositive end-expiratory pressureMechanical ventilationRandomized controlled trialIntensive care medicineCochrane LibraryEmergency medicineLungAnesthesiaInternal medicineRespiratory Support and MechanismsNeonatal Respiratory Health ResearchCardiac Arrest and Resuscitation