Side-chain halogen effects on self-assembly and hydrogelation of cationic phenylalanine derivatives
Brittany L. Abraham, Samantha G. Mensah, Benjamin R. Gwinnell, Bradley L. Nilsson
Abstract
positions of the phenyl side chain reveal significant differences in self-assembly and gelation potential, nanoscale assembly morphology, and hydrogel viscoelastic properties as a function of halogen identity and substitution position. These results demonstrate the profound impact that subtle changes to the chemical scaffold can have on the behavior of LMW supramolecular gelators and illustrate the ongoing difficulty of predicting the emergent self-assembly and hydrogelation behavior of LMW gelators that differ even modestly in chemical structure.
Topics & Concepts
Cationic polymerizationSide chainHalogenationChemistryHalogenPhenylalanineSelf-assemblyChain (unit)Polymer chemistryNanoscopic scaleOrganic chemistryNanotechnologyMaterials scienceAmino acidBiochemistryPolymerAlkylPhysicsAstronomySupramolecular Self-Assembly in MaterialsPolydiacetylene-based materials and applicationsLipid Membrane Structure and Behavior