Lignin–cellulose complexes derived from agricultural wastes for combined antibacterial and tissue engineering scaffolds for cutaneous leishmaniasis wounds
Marie Andrea Laetitia Huët, Itisha Chummun Phul, Nowsheen Goonoo, Zhikai Li, Xiaopeng Li, Archana Bhaw‐Luximon
Abstract
, with greater efficiency against Gram-negative strains. 3D hydrogels were engineered by crosslinking SCB lignin with SCB cellulose in varying weight ratios in the presence of epichlorohydrin. The stiffness of the hydrogels could be tailored by varying the lignin concentration. All hydrogels were biocompatible; however, better fibroblast adhesion was observed on the blended hydrogels compared to the 100% cellulose hydrogel, with the cellulose : lignin 70 : 30 hydrogel showing the highest L929 proliferation and best antibacterial properties with a 24-hour bacterial growth reduction ranging from 30.8 to 57.3%.
Topics & Concepts
LigninCelluloseCutaneous leishmaniasisMaterials sciencePulp and paper industryAgricultureLeishmaniasisMedicineOrganic chemistryChemistryBiologyEngineeringPathologyEcologyResearch on Leishmaniasis Studies