Identification of Microorganisms by Liquid Chromatography-Mass Spectrometry (LC-MS1) and in Silico Peptide Mass Libraries
Peter Lasch, Andy Schneider, Christian Blumenscheit, Joerg Doellinger
Abstract
peak lists obtained from 19 different microbial pathogens. The proposed method is rapid, simple and automatable and we foresee wide application potential for future microbiological applications.
Topics & Concepts
In silicoBottom-up proteomicsUniProtProteomicsComputational biologyMass spectrometryIdentification (biology)Tandem mass spectrometryPeptideDatabase search engineLiquid chromatography–mass spectrometryChemistryChromatographyBiologyComputer scienceBiochemistryProtein mass spectrometryInformation retrievalSearch engineBotanyGeneBacterial Identification and Susceptibility TestingYersinia bacterium, plague, ectoparasites researchGenomics and Phylogenetic Studies