Comparative pharmacokinetics of seven bioactive components after oral administration of crude and processed Qixue Shuangbu Prescription in chronic heart failure rats by microdialysis combined with UPLC-MS/MS
Linwei Chen, Nina Wei, Yong Jiang, Chengye Yuan, Luwei Xu, Jindong Li, Min Kong, Yan Chen, Qin Wang
Topics & Concepts
PharmacokineticsPaeoniflorinPharmacologyMicrodialysisOral administrationMedicineCmaxHigh-performance liquid chromatographyChemistryChromatographyInternal medicineCentral nervous systemTraditional Chinese Medicine AnalysisGinseng Biological Effects and ApplicationsChemotherapy-induced cardiotoxicity and mitigation