Determination of novel CYP2D6 haplotype using the targeted sequencing followed by the long-read sequencing and the functional characterization in the Japanese population
Koya Fukunaga, Eiji Hishinuma, Masahiro Hiratsuka, Ken Kato, Takuji Okusaka, Takeo Saito, Masashi Ikeda, Teruhiko Yoshida, Hitoshi Zembutsu, Nakao Iwata, Taisei Mushiroda
Topics & Concepts
HaplotypeCYP2D6BiologyGeneticsPopulationAlleleComputational biologyGeneGenotypeMedicineEnvironmental healthPharmacogenetics and Drug MetabolismRenal Transplantation Outcomes and TreatmentsDrug Transport and Resistance Mechanisms