Optimization of DOTAP/chol Cationic Lipid Nanoparticles for mRNA, pDNA, and Oligonucleotide Delivery
Mengwei Sun, Utkarsh J. Dang, Yuhao Yuan, Alexandra Maria Psaras, Ositomiwa O. Osipitan, Tracy A. Brooks, Fake Lu, Anthony J. Di Pasqua
Topics & Concepts
TransfectionPEGylationChemistryOligonucleotideNucleic acidGene deliveryMessenger RNAMolecular biologyBiophysicsBiochemistryBiologyGenePolyethylene glycolRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesVirus-based gene therapy research