First Experience of Radionuclide Therapy With 177Lu-FAPI-2286 in a Patient With Metastatic Mediastinal Sarcoma
Seyedeh Somayyeh Banihashemian, Mohadese Bayat, Elahe Pirayesh, Ghasemali Divband, Abdolghafar Abolhosseini, Mohammad Esmaeel Akbari
Abstract
ABSTRACT: Fibroblast activation protein (FAP) is a new promising molecular target for theragnostic approach. FAP inhibitors (FAPIs) labeled with 177Lu could be potentially a therapeutic radiopharmaceutical. Here, we presented the experience of 4 cycles of 177Lu-FAPI in a 67-year-old man with an unresectable mediastinal sarcoma.
Topics & Concepts
MedicineRadionuclide therapySarcomaRadiologyRadionuclideNuclear medicinePathologyQuantum mechanicsPhysicsPeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairProtease and Inhibitor Mechanisms