Upregulation of microRNA-195 ameliorates calcific aortic valve disease by inhibiting VWF via suppression of the p38-MAPK signaling pathway
Lieming Yang, Dawei Wu, Mengqi Li, Xinyuan Zhu, Yikui Tian, Zhi Chen, Mingbiao Li, Hao Zhang, Degang Liang
Topics & Concepts
MedicineDownregulation and upregulationCalcificationRUNX2Gene silencingmicroRNAp38 mitogen-activated protein kinasesCancer researchSignal transductionMAPK/ERK pathwayInternal medicineEndocrinologyCell biologyBiologyIn vitroOsteoblastBiochemistryGeneCardiac Valve Diseases and TreatmentsParathyroid Disorders and TreatmentsMicroRNA in disease regulation