Engineering adipic acid metabolism in Pseudomonas putida
Yannic S. Ackermann, Wing‐Jin Li, Leonie Op de Hipt, Paul-Joachim Niehoff, William Casey, Tino Polen, Sebastian Köbbing, Hendrik Ballerstedt, Benedikt Wynands, Kevin E. O’Connor, Lars M. Blank, Nick Wierckx
Abstract
. In a nitrogen-limited medium this strain produced polyhydroxyalkanoates from adipate up to 25% of its CDW. This proves its applicability for the upcycling of mixtures of polymers made from fossile resources into biodegradable counterparts.
Topics & Concepts
Pseudomonas putidaAdipic acidMetabolismMetabolic engineeringBiochemistryChemistryOrganic chemistryEnzymeBacterial biofilms and quorum sensingMicrobial Metabolic Engineering and BioproductionBacterial Genetics and Biotechnology