A cold-water extracted polysaccharide-protein complex from Grifola frondosa exhibited anti-tumor activity via TLR4-NF-κB signaling activation and gut microbiota modification in H22 tumor-bearing mice
Jiahui Zhao, Rongjun He, Hao Zhong, Shizhu Liu, Xiaofeng Liu, Muhammad Hussain, Peilong Sun
Topics & Concepts
Grifola frondosaTLR4ChemistryIn vivoSecretionDownregulation and upregulationPolyglutamic acidGut floraPolysaccharideBiochemistryBiologySignal transductionGeneBiotechnologyGut microbiota and healthSeaweed-derived Bioactive CompoundsProbiotics and Fermented Foods