Phthalimides: developments in synthesis and functionalization
Fatemeh Doraghi, Mohammad Hossein Morshedsolouk, Nawrooz Ali Zahedi, Bagher Larijani, Mohammad Mahdavi
Abstract
Phthalimides, an important class of biologically active N-heterocycles, are not only found in pharmaceuticals, natural products, agrochemicals, polymers, and dyes, but also serve as building blocks in organic transformations. Many synthetic methods, including metal catalysis and metal-free systems, have been developed to prepare functionalized phthalimides. In this review, we describe the developments in the synthesis and functionalization of phthalimides over the past two decades.
Topics & Concepts
PhthalimidesSurface modificationChemistryCombinatorial chemistryPhthalimideOrganic chemistryPhysical chemistryClick Chemistry and ApplicationsProtein Degradation and InhibitorsSynthesis and Catalytic Reactions