E3 ubiquitin ligase SMURF2 prevents colorectal cancer by reducing the stability of the YY1 protein and inhibiting the SENP1/c-myc axis
Qianfu Gao, Shanchao Wang, Zeyan Zhang
Topics & Concepts
YY1Ubiquitin ligaseDownregulation and upregulationCancer researchUbiquitinWestern blotColorectal cancerBiologyTransfectionMolecular biologyCancerCell cultureGene expressionGenePromoterBiochemistryGeneticsUbiquitin and proteasome pathwaysRNA modifications and cancerCancer-related molecular mechanisms research