Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2
Hongwu Qian, Xuelan Wu, Ximing Du, Xia Yao, Xin Zhao, Joyce Lee, Hongyuan Yang, Nieng Yan
Topics & Concepts
NPC1CholesterolBiologyTransmembrane domainTransmembrane proteinSterolDomain (mathematical analysis)BiophysicsMembraneBiochemistryEndosomeReceptorMathematical analysisMathematicsLysosomal Storage Disorders ResearchCalcium signaling and nucleotide metabolismCytomegalovirus and herpesvirus research