Genetic in vivo engineering of human T lymphocytes in mouse models
Tatjana Weidner, Shiwani Agarwal, Séverine Perian, Floriane Fusil, Gundula Braun, Jessica Hartmann, Els Verhoeyen, Christian J. Buchholz
Topics & Concepts
Chimeric antigen receptorCD8Gene deliveryBiologyFlow cytometryGene targetingStem cellHaematopoiesisIn vivoViral vectorGenetic enhancementComputational biologyHematopoietic stem cellReceptorT cellMolecular biologyCell biologyAntigenImmunologyGeneRecombinant DNAGeneticsImmune systemCAR-T cell therapy researchVirus-based gene therapy researchViral Infectious Diseases and Gene Expression in Insects