Improved AP-3 production through combined ARTP mutagenesis, fermentation optimization, and subsequent genome shuffling
Juan Li, Siyu Guo, Qiang Hua, Fengxian Hu
Topics & Concepts
FermentationMutagenesisMutantStrain (injury)BiologyDNA shufflingMicrobiologyGeneBiotechnologyBiochemistryDirected evolutionAnatomyMicrobial Natural Products and BiosynthesisGenomics and Phylogenetic StudiesMarine Sponges and Natural Products