Silver salt enabled H/D exchange at the β-position of thiophene rings: synthesis of fully deuterated thiophene derivatives
Fei-Fei Sheng, En‐Ci Li, Jingwen Bai, Caixia Wang, Guang-Qi Hu, Kaihui Liu, Zhengyi Sun, Kang Shen, Honghai Zhang
Abstract
O as the deuterium source, good tolerance to a range of functional groups and obtaining high atom% deuterium incorporation. In addition, this H/D exchange reaction is employed for direct deuteration of a thiophene based monomer, which is usually prepared by multistep synthesis from expensive deuterated starting materials.
Topics & Concepts
ThiopheneChemistryDeuteriumAtom (system on chip)Salt (chemistry)MonomerMoleculePhotochemistryCombinatorial chemistryOrganic chemistryPolymerComputer scienceQuantum mechanicsEmbedded systemPhysicsChemical Reactions and IsotopesAsymmetric Hydrogenation and CatalysisChemical Reaction Mechanisms