Preparation of COF-coated nickel foam adsorbents for dispersive solid-phase extraction of 16 polycyclic aromatic hydrocarbons from Chinese herbal medicines
Yang Li, Zhihong Yan, Jiahua Fan, Xuelian Yao, Ying Cai
Abstract
Covalent organic framework coated nickel foam (NF@COF) was prepared as a sorbent for the dispersive solid phase extraction (DSPE) of polycyclic aromatic hydrocarbons (PAHs) from Chinese herbal medicines (CHMs) prior to their determination by gas chromatography-mass spectrometry (GC-MS). The structure and morphology of the as-synthesized NF@COF were characterized by different techniques. Various key parameters affecting the performance of the DSPE method , including the amount of sorbent , desorption solvent, desorption volume and time, extraction time, and sample volume, were investigated. Under the optimized conditions, NF@COF combined with GC-MS was successfully applied to the determination of 16 PAHs in CHMs. The method showed wide linearity (20–2000 ng mL −1 ), low limits of determination (0.3–2.7 ng mL −1 ), and high recoveries (78.0–124%). These results revealed that NF@COF has the potential for efficient extraction of PAHs from complex samples.