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Microfluidic chips in female reproduction: a systematic review of status, advances, and challenges

Tong Wu, Jinfeng Yan, Kebing Nie, Ying Chen, Yangyang Wu, Shixuan Wang, Jinjin Zhang

2024Theranostics22 citationsDOIOpen Access PDF

Abstract

organs, mostly involved in placenta and fetal membrane research. Fourteen studies perform drug screening and toxicity testing. In this review, we summarize the current application of microfluidic chips in studying the female reproductive system, the advancements in materials and methods, and discuss the future challenges. The present evidence suggests that microfluidic chips-assisted reproductive system reconstruction is promising and more studies are urgently needed.

Topics & Concepts

Assisted reproductive technologyBiologyMedicineBioinformaticsPregnancyInfertilityGeneticsReproductive Biology and FertilityOvarian function and disordersAssisted Reproductive Technology and Twin Pregnancy