Studies on ligand-based pharmacophore modeling approach in identifying potent future EGFR inhibitors

Gulam Moin Shaikh, Manikanta Murahari, Shikha Thakur, Maushmi S. Kumar, Mayur YC

2021Journal of Molecular Graphics and Modelling18 citationsDOI

Topics & Concepts

PharmacophoreIn silicoComputational biologyEGFR inhibitorsOsimertinibQuantitative structure–activity relationshipEpidermal growth factor receptorLigand (biochemistry)Drug discoveryChemistryRational designCombinatorial chemistryBiologyStereochemistryReceptorBiochemistryErlotinibGeneticsGeneCancer therapeutics and mechanismsComputational Drug Discovery MethodsSynthesis and biological activity