Silibinin ameliorates cisplatin-induced acute kidney injury via activating Nfe2l1-mediated antioxidative response to suppress the ROS/MAPK signaling pathway
Fang Yang, Man Jia, Chengfeng Deng, Bin Xiao, Rongyang Dai, Yuancai Xiang
Topics & Concepts
SilibininCisplatinNephrotoxicityPharmacologyMAPK/ERK pathwayChemistrySignal transductionCancer researchKidneyMedicineBiochemistryChemotherapyInternal medicineChemotherapy-induced organ toxicity mitigationBiomedical Research and PathophysiologyArsenic contamination and mitigation