Intranasal repaglinide-solid lipid nanoparticles integrated in situ gel outperform conventional oral route in hypoglycemic activity
Soha M. Elkarray, Ragwa M. Farid, Mohammad M. Abd‐Alhaseeb, Gamal A. Omran, Doaa A. Habib
Topics & Concepts
Solid lipid nanoparticleRepaglinidePoloxamerNasal administrationPoloxamer 407Materials sciencePharmacologyGellan gumParticle sizeIn vivoDrug deliveryOral administrationChromatographyMedicineDrugType 2 diabetesChemistryDiabetes mellitusNanotechnologyCopolymerEndocrinologyPhysical chemistryBiotechnologyBiologyComposite materialFood sciencePolymerAdvanced Drug Delivery SystemsAdvancements in Transdermal Drug DeliveryLipid Membrane Structure and Behavior