Strategies for Biomolecular Analysis and Continuous Physiological Monitoring
Amanda Clifford, Jagotamoy Das, Hanie Yousefi, Alam Mahmud, Jenise B. Chen, Shana O. Kelley
Abstract
sensors capable of real-time monitoring of biomarkers such as nucleic acids, proteins, viral particles, bacteria, therapeutic agents, and metabolites, will be discussed. Reagentless platforms which allow for wash-free, calibration free-detection with increased dynamic range are highlighted as a key technological advance for autonomous sensing applications. Furthermore, we will highlight remaining challenges which must be overcome to enable widespread use of reagentless devices. Finally, future prospects and potential breakthroughs in precision medicine that will arise as a result of further development of reagentless sensing approaches are discussed.
Topics & Concepts
Biochemical engineeringNanotechnologyComputer scienceRisk analysis (engineering)Systems engineeringEngineeringMedicineMaterials scienceBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniquesAnalytical Chemistry and Sensors