Phoenix dactylifera L. (date palm) fruit extracts and fractions exhibit anti-proliferative activity against human pancreatic cancer cell lines
Reem A Al Alawi, Jörg D. Hoheisel, Mohamed Saiel Saeed Alhamdani, Younis Baqi
Abstract
-butanol fraction tested at 500 μg/mL. Moreover, sub-fractions obtained from the ethyl acetate extract inhibited pancreatic cancer cell proliferation, especially fraction EA-III-2 tested at 50-150 μg/mL. These findings suggest that date fruit extracts contain nutraceuticals with potential therapeutic value in the treatment of pancreatic cancer. Future work will be focused on isolation and identification of the active compounds and explore their mechanisms of action.
Topics & Concepts
Phoenix dactyliferaPalmPancreatic cancerCell cultureTraditional medicineBiologyBotanyCancerMedicineGeneticsQuantum mechanicsPhysicsDate Palm Research StudiesGenetic and Environmental Crop StudiesInsect Pest Control Strategies