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An overview of screening instruments for cognition and behavior in patients with ALS: selecting the appropriate tool for clinical practice

Isabel K. Gosselt, Tanja C.W. Nijboer, Michael A. van Es

2020Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration62 citationsDOIOpen Access PDF

Abstract

Considering the broad range of cognitive domains, adaptability, and satisfying validity, the ALS-CBS and ECAS appear to be the most suitable screeners to detect cognitive and behavioral changes in ALS. The BBI appears to be the best option to screen for behavioral changes in ALS, since all relevant domains are assessed, motor-related problems are considered, and has a satisfactory validity. The MiND-B and ALS-FTD-Q are promising as well. In general, all screening instruments would benefit from additional validation research to gain greater insights into test characteristics and to aid clinicians in selecting screening tools for use in clinical practice.

Topics & Concepts

Amyotrophic lateral sclerosisCognitionNeuropsychologyPsychologyPhysical medicine and rehabilitationMEDLINEClinical psychologyMedicinePsychiatryDiseasePathologyLawPolitical scienceAmyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research