Iridium(III)-Catalyzed Regioselective B(4)–H Amination of <i>o</i>-Carboranes with Sufilimines
Kyeongna Park, Gi Uk Han, S.‐K. YOON, Eunseo Lee, Hee Chan Noh, Kyungsup Lee, Chanyoung Maeng, Dongwook Kim, Phil Ho Lee
Abstract
Iridium(III)-catalyzed regioselective B(4)–H amination is developed from the reaction of o -carborane acids with sulfilimines without any oxidants under mild conditions, which leads to a wide range of B(4)–H aminated o -carboranes in good yields with a broad substrate scope. Moreover, the selective B(3,6)-diamination reaction of the o -carborane acid was achieved. The present reaction is attractive from a practical point of view because dibenzothiophene is quantitatively recovered and reused.
Topics & Concepts
RegioselectivityChemistryAminationIridiumDibenzothiopheneCatalysisSubstrate (aquarium)Combinatorial chemistryCarboraneMedicinal chemistryOrganic chemistryGeologyOceanographyBoron Compounds in ChemistryPharmacological Effects and Toxicity StudiesOrthopedic Infections and Treatments