Electrophilic Reagents for the Direct Incorporation of Uncommon SCF <sub>2</sub> CF <sub>2</sub> H and SCF <sub>2</sub> CF <sub>3</sub> Motifs
Jordi Mestre, Miguel Bernús, Sergio Castillón, Omar Boutureira
Abstract
motifs. Their reactivity performance, multigram-scale preparation, and divergent derivatization have been thoroughly investigated with a variety of nucleophiles, including natural products and pharmaceuticals.
Topics & Concepts
ElectrophileReagentCombinatorial chemistryChemistryComputational chemistryOrganic chemistryCatalysisFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsSynthesis and Reactions of Organic Compounds