Tyrosine-modified linear PEIs for highly efficacious and biocompatible siRNA delivery in vitro and in vivo
Michael Karimov, Marion Schulz, Tim Kahl, Sandra Noske, Małgorzata Kubczak, I Gockel, René Thieme, Thomas Büch, Anja Reinert, Максим Йонов, Maria Bryszewska, Heike Franke, Ute Krügel, Alexander Ewe, Achim Aigner
Topics & Concepts
Small interfering RNAGene knockdownIn vivoGene silencingIn vitroRNA interferenceTransfectionBiocompatibilityEx vivoChemistryCancer researchMolecular biologyBiologyRNABiochemistryGeneBiotechnologyOrganic chemistryRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesDendrimers and Hyperbranched Polymers