Ticagrelor causes false-negative functional tests for heparin-induced thrombocytopenia
Julia J.M. Eekels, Christoph Pachler, Nora Krause, Tina Muhr, Gert Waltl, Andreas Greinacher
Abstract
Heparin-induced thrombocytopenia (HIT) occurs in 1-2% of patients with acute coronary events or cardiac surgery. Eekels and colleagues report that ticagrelor comedication must be taken into account by laboratory physicians for interpretation of functional tests for HIT, as the presence of the drug can cause false-negative results.
Topics & Concepts
Heparin-induced thrombocytopeniaTicagrelorMedicineHeparinAcute coronary syndromeInternal medicineCardiologyIntensive care medicineMyocardial infarctionHeparin-Induced Thrombocytopenia and ThrombosisAntiplatelet Therapy and Cardiovascular DiseasesIntramuscular injections and effects