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Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands

Daniel N. Weinberg, Phillip Rosenbaum, Xiao Chen, Douglas Barrows, Cynthia Horth, Matthew R. Marunde, Irina K Popova, Zachary B Gillespie, Michael‐Christopher Keogh, Chao Lü, Jacek Majewski, C. David Allis

2021Nature Genetics107 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDNA methylationEZH2HistoneHistone H3EpigeneticsCpG siteHistone methylationGeneticsEpigenomicsMethylationCell biologyCancer epigeneticsHistone methyltransferaseDNAGeneGene expressionEpigenetics and DNA MethylationCancer-related gene regulationGenetics and Neurodevelopmental Disorders
Two competing mechanisms of DNMT3A recruitment regulate the dynamics of de novo DNA methylation at PRC1-targeted CpG islands | Litcius