Resident memory T cells form during persistent antigen exposure leading to allograft rejection
Khodor I. Abou‐Daya, Roger Tieu, Daqiang Zhao, Rayan Rammal, Faruk Sacirbegovic, Amanda Williams, Warren D. Shlomchik, Martin H. Oberbarnscheidt, Fadi G. Lakkis
Abstract
Recipient effector T cells differentiate into functional tissue-resident memory T cells, causing graft rejection after kidney transplantation.
Topics & Concepts
EffectorAntigenImmunologyTransplantationKidneyImmunological memoryBiologyMedicineImmune systemImmunityInternal medicineGeneticsImmune Cell Function and InteractionT-cell and B-cell ImmunologyCytomegalovirus and herpesvirus research