Development of an Effective Nontoxigenic Clostridioides difficile–Based Oral Vaccine against C. difficile Infection
Shaohui Wang, Duolong Zhu, Xingmin Sun
Abstract
Clostridioides difficile is an enteric pathogen, and symptoms of C. difficile infection (CDI) are mainly by two exotoxins TcdA and TcdB. Active vaccination is cost-effective approach to prevent CDI and high rates of recurrence.
Topics & Concepts
ClostridioidesMedicineMicrobiologyBiologyVirologyClostridium difficile and Clostridium perfringens researchViral gastroenteritis research and epidemiologyMicroscopic Colitis